The critically acclaimed Dr Semmelweis was originally developed by the National Theatre Studio and produced by Bristol Old Vic, opening on 20 January 2022 in association with Sonia Friedman Productions, the National Theatre, and Shakespeare Road. The play, in which Rylance reprises the title role, is written by Stephen Brown with Mark Rylance and is directed by Tom Morris. In a unique theatrical event, he and the cast are joined on stage by 10 ballet dancers and the Salome String Quartet. The company are: Roseanna Anderson (Marja Seidel/ Baroness Maria-Teresa), Zoe Arshamian (Dance Ensemble), Joshua Ben-Tovim (Hospital Porter/ Death), Ewan Black (Franz Arneth), Chrissy Brooke (Lisa Elstein), Megumi Eda (Aiko Eda), Suzy Halstead (Violet-May Blackledge), Felix Hayes (Ferdinand von Hebra), Pauline McLynn (Anna Müller), Jude Owusu (Jakob Kolletschka), Oxana Panchenko (Dance Ensemble), Millie Thomas (Agnes Barta), Max Westwell (Hospital Porter/ Death), Amanda Wilkin (Maria Semmelweis), Alan Williams (Johann Klein), Daniel York Loh (Karl von Rokitansky), Patricia Zhou (Dance Ensemble), and Helen Belbin, Jason Hogan, Andrew McDonald, with the Salomé Quartet - Haim Choi as Suk Hee Apfelbaum (Music Director/ Violin 1), Coco Inman as Sarah Schmidt (Violin 2), Kasia Zimińska as Eszter Horowitz (Viola) and Shizuku Tatsuno as Oshizu Yukimura (Cello).